Isocyanate-induced occupational asthma: immunologic and challenge studies.
نویسندگان
چکیده
منابع مشابه
Isocyanate-induced occupational asthma: challenge and immunologic studies.
Isocyanate is the most prevalent agent in occupational asthma(OA) in Korea. We analyzed 43 toluene diisocyanate(TDI) induced OA patients of whom 81% were found to be spray painters. The bronchial sensitivity of all subjects was confirmed by TDI-bronchial challenge test. Serum-specific IgE antibodies to isocyanate-human serum albumin(HSA) conjugate were detected by RAST technique(Pharmacia, Swed...
متن کاملOutcome determinants for isocyanate induced occupational asthma among compensation claimants.
OBJECTIVES To compare the outcome of occupational asthma (OA) induced by isocyanates in Ontario (where a surveillance programme for exposed workers has been in place for over 15 years), with the outcome of OA induced by other work agents. METHODS Compensated OA claims during the period 1984-88 in Ontario were retrospectively reviewed in a standardised way. RESULTS 136/235 compensated claims...
متن کاملPrevention Guidance for Isocyanate-Induced Asthma Using Occupational Surveillance Data
Data from Washington State's work-related asthma surveillance system were used to characterize isocyanate-induced asthma cases occurring from 1999 through 2010. Injured worker interviews and medical records were used to describe the industry, job title, work process, workers' compensation cost, and exposure trends associated with 27 cases of isocyanate-induced asthma. The majority (81%) of case...
متن کاملBiomarkers Predicting Isocyanate-Induced Asthma
THREE DIISOCYANATES CAN CAUSE OCCUPATIONAL ASTHMA (OA): toluene diisocyanate (TDI), 4,4 diphenylmethane diisocyanate (MDI), and 1,6-hexamethylene diisocyanate (HDI). We analyzed potential biomarkers of isocyanate-induced OA, based on investigated immunologic, genetic, neurogenic, and protein markers, because there is no serological testing method. The prevalence of serum IgG to cytokeratin (CK)...
متن کاملIsocyanate exposure and occupational asthma: a case-referent study.
OBJECTIVE To examine the quantitative relation between exposure to isocyanates and occupational asthma, and to explore the role of atopy and smoking in occurrence of the disease. METHOD A case-referent study was undertaken of cases from two manufacturing companies (A and B) from which referents without disease could be selected and reliable exposure measurements were available. In company A, ...
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ژورنال
عنوان ژورنال: Tuberculosis and Respiratory Diseases
سال: 1992
ISSN: 1738-3536,2005-6184
DOI: 10.4046/trd.1992.39.6.490